(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride → HCID 70401137, compound

HRID 2118708Notes

Reaction equation

HRID 2118708 reaction equation
[ClH:1].O[CH:3]1[O:11][C@H:10]([CH2:12][OH:13])[C@@H:8]([OH:9])[C@H:6]([OH:7])[C@H:4]1[NH2:5]>C(N)CC>[ClH:1].[CH2:4]([NH:5][CH:3]1[O:11][C@H:10]([CH2:12][OH:13])[C@@H:8]([OH:9])[C@H:6]([OH:7])[C@H:4]1[NH2:5])[CH2:6][CH3:8]

Participants

3

Reactant 1

HCID 2723635(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride

Product 1

HCID 70401137HCID 70401137, compound

Reagents, catalysts & solvents 1

HCID 7852PropylamineSolvent

Conditions

Temperature
70 °C

Procedure

21.5 g of glucosamine hydrochloride are suspended in 17.7 g of n-propylamine and heated at 70° C. until a clear solution is produced. On cooling to room temperature, the product precipitated out.

Workup

  1. customis produced
  2. temperatureOn cooling to room temperature
  3. customthe product precipitated out

Sources & evidence

ORD record
ord-60988b8057e84e62becc58d8228a3356
Source dataset
uspto-grants-1987_07
Patent number
US04680287

Reaction notes

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