Calcium Carbonate → HCID 15072476, compound

HRID 2118817Notes

Reaction equation

HRID 2118817 reaction equation
Cl[C:2]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[CH:8][C:7]=1[Cl:13])=[O:5].[CH3:21][CH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1.C(=O)([O-])[O-].[Ca+2]>C(O)C>[CH3:21][CH:22]1[CH2:27][CH2:26][N:25]([C:2]2[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][C:3]=2[C:4]([C:6]2[CH:11]=[CH:10][C:9]([Cl:12])=[CH:8][C:7]=2[Cl:13])=[O:5])[CH2:24][CH2:23]1

Participants

5

Reactant 3

HCID 10112Calcium CarbonateHCID 693814-MethylpiperidineHCID 15072475(2-Chloro-5-nitrophenyl)(2,4-dichlorophenyl)methanone

Product 1

HCID 15072476HCID 15072476, compoundYield 75%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Proceeding as indicated in example 2, with 0.053 mole (17.5 g) of 2,2',4'-trichloro-5-nitro-benzophenone, 0.088 mole (8.8 g) of 4-methylpiperidine and 0.0712 mole (9.8 g) of calcium carbonate in 50 cm3 of ethanol, 15.5 g (Yield: 75%) of the expected product are obtained after re-crystallization in a mixture of isopropyl ether and toluene (70 v./30 v.) M.P.: 103° C.

Sources & evidence

ORD record
ord-a01c0a66fa2c49968753c2718491e781
Source dataset
uspto-grants-1987_07
Patent number
US04680402

Reaction notes

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