Potassium Cation → {4-[2-(2,4-Dichloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-2-oxo-2H-pyridin-1-yl}-acetic acid methyl ester

HRID 211908Notes

Reaction equation

HRID 211908 reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:24][C:25]([CH3:26])([O-:27])[CH3:28].[CH3:30][O:31][C:32]([CH2:33][Br:34])=[O:35].[Cl:1][c:2]1[c:3]([CH:9]([C:10]([C:11]([F:12])([F:13])[F:14])([OH:15])[c:16]2[cH:17][c:18](=[O:22])[nH:19][cH:20][cH:21]2)[CH3:23])[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[K+:29].[OH2:36]>>[Cl:1][c:2]1[c:3]([CH:9]([C:10]([C:11]([F:12])([F:13])[F:14])([OH:15])[c:16]2[cH:17][c:18](=[O:22])[n:19]([CH2:33][C:32]([O:31][CH3:30])=[O:35])[cH:20][cH:21]2)[CH3:23])[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

7

Reactant 6

HCID 813Potassium CationHCID 962WaterHCID 8028TetrahydrofuranHCID 60984Methyl bromoacetateHCID 45749132-Methylpropan-2-olateHCID 57421256HCID 57421256, compound

Product 1

HCID 25254607{4-[2-(2,4-Dichloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-2-oxo-2H-pyridin-1-yl}-acetic acid methyl ester

Sources & evidence

ORD record
ord-5898b28a0d5d42aab71758f03ce864cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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