反应详情

温度

50 °C

A suspension of 50 g (342 mmol) phthalazone, 1370 ml acetonitrile, 66 ml (0.72 mol) POCl3 and 85 ml 4 N HCl in dioxane is stirred for 8 h at 50° C. The resulting solution is cooled to RT, evaporated to a volume of about 0.8 l and diluted with 1.2 l DIPE. Filtration and washing with DIPE yield the title compound: FAB-MS (M+H)+=165/167.

1. temperatureThe resulting solution is cooled to RT
2. customevaporated to a volume of about 0.8 l
3. additiondiluted with 1.2 l DIPE
4. filtrationFiltration
5. washwashing with DIPE