反应详情

温度

100 °C

A mixture of 1.48 g (6.35 mmol) (3-Thioureido-propyl)-carbamic acid tert-butyl ester and 15 ml Dimethylformamide dimethyl acetal was heated to 100° C. for 16 h. The mixture was concentrated and the residue was purified by flash column chromatography on silica eluting with ethyl acetate/n-hexane 1/1 to yield 1.65 g (90%) of the title compound.

1. concentrationThe mixture was concentrated
2. customthe residue was purified by flash column chromatography on silica eluting with ethyl acetate/n-hexane 1/1