Acetic Acid → HCID 86759335, compound

HRID 2120431Notes

Reaction equation

O1CCCCC1C1C=C([CH:20]=[CH:21][C:22]2[CH:27]=[CH:26][C:25]([CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][C:33]([CH3:42])([CH3:41])[O:34]C3CCCCO3)=[CH:24][CH:23]=2)C=C(OC2CCCCO2)C=1.[C:43](O)(=O)[CH3:44].[CH2:47]1[CH2:51][O:50][CH2:49][CH2:48]1.[OH2:52]>>[OH:34][C:33]([CH3:42])([CH3:41])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][C:25]1[CH:26]=[CH:27][C:22]([CH:21]=[CH:20][C:47]2[C:48]([OH:52])=[CH:49][CH:44]=[CH:43][C:51]=2[OH:50])=[CH:23][CH:24]=1

Participants

Reactant 4

HCID 176Acetic Acid

HCID 962Water

HCID 8028Tetrahydrofuran

HCID 69927359HCID 69927359, compound

Product 1

HCID 86759335HCID 86759335, compound

Procedure

In a manner similar to Example 8(k), by reacting 4.98 g (8.4 mmol) of 2-[6-(4-{2-[3-(tetrahydropyran-2-yl)-5-(tetrahydropyran-2-yloxy)phenyl]-vinyl}phenyl)-1,1-dimethylhexyloxy]tetrahydropyran with the solution of 100 ml of acetic acid, 50 ml of THF and 25 ml of water, whitish crystals (m=1.85 g; Y=65%) are obtained. m.p.=158-60° C.

Workup

customare obtained

Sources & evidence

ORD record: ord-38b7d528b4554111a0ca71c770c78dad
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06689922B1

Reaction notes

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