Tetrabutylammonium Fluoride → HCID 67278732, compound

HRID 2120448Notes

Reaction equation

HRID 2120448 reaction equation
[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:25]=[CH:26][C:27]2[CH:28]=[C:29]([CH2:33][CH2:34][CH2:35][CH2:36][C:37]([CH3:40])([OH:39])[CH3:38])[CH:30]=[CH:31][CH:32]=2)[CH:13]=[C:14]([CH2:16][O:17][Si](C(C)(C)C)(C)C)[CH:15]=1)(C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>C1COCC1>[OH:17][CH2:16][C:14]1[CH:13]=[C:12]([CH:25]=[CH:26][C:27]2[CH:28]=[C:29]([CH2:33][CH2:34][CH2:35][CH2:36][C:37]([CH3:40])([OH:39])[CH3:38])[CH:30]=[CH:31][CH:32]=2)[CH:11]=[C:10]([CH2:9][OH:8])[CH:15]=1

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 69685730HCID 69685730, compound

Product 1

HCID 67278732HCID 67278732, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 3(i), by reacting 858 mg (1.47 mmol) of 6-(3-{2-[3,5-bis-(tert-butyldimethylsilanyloxymethyl)phenyl]vinyl}phenyl)-2-methylhexan-2-ol with 3.25 ml of tetrabutylammonium fluoride 1M/THF, after purification on a silica column (ethyl acetate), a white paste (m=460 mg; Y=88%) is obtained.

Workup

  1. customafter purification on a silica column (ethyl acetate)
  2. customa white paste (m=460 mg; Y=88%) is obtained

Sources & evidence

ORD record
ord-c17a463bfb1c41c9bcf935a3c494b40b
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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