Sulfuric Acid → HCID 57068259, compound

HRID 2120458Notes

Reaction equation

HRID 2120458 reaction equation
S(=O)(=O)(O)O.C(OC[O:10][C:11]1[CH:12]=[C:13]([CH:22]=[CH:23][C:24]2[CH:25]=[C:26]([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][OH:35])[CH:27]=[CH:28][CH:29]=2)[CH:14]=[C:15]([O:17]COCC)[CH:16]=1)C>CO.C1COCC1>[OH:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][C:26]1[CH:25]=[C:24]([CH:23]=[CH:22][C:13]2[CH:12]=[C:11]([OH:10])[CH:16]=[C:15]([OH:17])[CH:14]=2)[CH:29]=[CH:28][CH:27]=1

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 57166925HCID 57166925, compound

Product 1

HCID 57068259HCID 57068259, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolvent2×HCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 1(j), by reacting 0.1 ml of concentrated sulphuric acid in 1 ml of methanol with 90 mg (0.2 mmol) of 5-{3-[2-(3,5-bis-ethoxymethoxyphenyl)vinyl]phenyl}pentan-1-ol in 1 ml of methanol and 1 ml of THF, after purification on a silica column (ethyl acetate 60-heptane 40), a white powder (m=33 mg; Y=55%) is obtained.

Workup

  1. customafter purification on a silica column (ethyl acetate 60-heptane 40)
  2. customa white powder (m=33 mg; Y=55%) is obtained

Sources & evidence

ORD record
ord-d8662ed1193b41f086f35410acdcc491
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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