Hydrochloric Acid → HCID 21954458, compound

HRID 2120529Notes

Reaction equation

HRID 2120529 reaction equation
[C:1]([O:6][C:7]([C:10]12[CH2:19][C:14]3([O:20]COCCOC)[CH2:15][CH:16]([CH2:18][C:12]([O:27]COCCOC)([CH2:13]3)[CH2:11]1)[CH2:17]2)([CH3:9])[CH3:8])(=[O:5])[C:2]([CH3:4])=[CH2:3].Cl.[Cl-].[NH4+]>CC(C)=O>[OH:20][C:14]12[CH2:19][C:10]3([C:7]([O:6][C:1](=[O:5])[C:2]([CH3:4])=[CH2:3])([CH3:9])[CH3:8])[CH2:17][CH:16]([CH2:18][C:12]([OH:27])([CH2:11]3)[CH2:13]1)[CH2:15]2

Participants

5

Reactant 3

HCID 313Hydrochloric Acid2×HCID 25517Ammonium ChlorideHCID 23435157HCID 23435157, compound

Product 1

HCID 21954458HCID 21954458, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 10 mmole of 1-(1-methacryloyloxy-1-methylethyl)-3,5-bis(2-methoxyethoxymethoxy)adamantane thus obtained, 1 mmole (in terms of HCl) of 6N-HCl and 40 ml of acetone was stirred at room temperature for 5 hours. The resulting reaction mixture was incorporated with an aqueous ammonium chloride solution, was extracted with ethyl acetate, the organic layer was concentrated, and the concentrate was subjected to column chromatography on a silica gel to thereby yield the title compound.

Workup

  1. customthus obtained
  2. customThe resulting reaction mixture
  3. extractionwas extracted with ethyl acetate
  4. concentrationthe organic layer was concentrated

Sources & evidence

ORD record
ord-1d8778a356d547f58f239beb3a33d04d
Source dataset
uspto-grants-2004_02
Patent number
US06692889B1

Reaction notes

Loading…