Triethylamine → HCID 20622482, compound

HRID 2120655Notes

Reaction equation

HRID 2120655 reaction equation
[CH2:1]([O:5][C:6](=[O:21])[CH2:7][CH2:8][C:9]#[C:10][C:11]1[CH:12]=[CH:13][C:14]2[O:15][CH2:16][CH2:17][NH:18][C:19]=2[N:20]=1)[CH2:2][CH2:3][CH3:4].C(N(CC)CC)C>CCO.O=[Pt]=O>[CH2:1]([O:5][C:6](=[O:21])[CH2:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:12]=[CH:13][C:14]2[O:15][CH2:16][CH2:17][NH:18][C:19]=2[N:20]=1)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 2

HCID 8471TriethylamineHCID 20622481HCID 20622481, compound

Product 1

HCID 20622482HCID 20622482, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 702EthanolSolvent

Procedure

A mixture of 4-5 (0.0643 g, 0.223 mmol), triethylamine (0.0169 g, 0.167 mmol), and PtO2 (0.0064 g) in EtOH (3.0 mL) was stirred under a hydrogen balloon for four hours. The reaction was filtered through Celite and concentrated to yield a cloudy, colorless oil.

Workup

  1. filtrationThe reaction was filtered through Celite
  2. concentrationconcentrated
  3. customto yield a cloudy, colorless oil

Sources & evidence

ORD record
ord-21f00170443d42e495bac0325860ec3d
Source dataset
uspto-grants-2004_02
Patent number
US06693101B2

Reaction notes

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