反应详情

To a solution of 23-7 (0.49 g, 1.5 mmol) and 2-methyl-pyrimidine-5-carbaldehyde (0.183 g, 1.5 mmol) in 15 mL DMF was added K2CO3 (0.310 g, 2.25 mmol). The mixture was stirred at ambient temperature for 2 hr and concentrated to a paste. The residue was purified by PCTLC (0-10% MeOH/CH2Cl2) which provided 0.400 g (83% yield) of 23-8.

1. concentrationconcentrated to a paste
2. customThe residue was purified by PCTLC (0-10% MeOH/CH2Cl2) which