Tetrahydrofuran → 4-(tert-butyl)-N-[3-(2-[{5-chloro-2-pyrimidinyl}oxy]ethoxy)-1-(2-hydroxyethyl)-4-(4-methylphenyl)-1H-pyrazol-5-yl]benzenesulfonamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([S:11](=[O:12])(=[O:13])[NH:14][c:15]2[c:16](-[c:41]3[cH:42][cH:43][c:44]([CH3:47])[cH:45][cH:46]3)[c:17]([O:30][CH2:31][CH2:32][O:33][c:34]3[n:35][cH:36][c:37]([Cl:40])[cH:38][n:39]3)[n:18][n:19]2[CH2:20][CH2:21][O:22][Si:23]([C:24]([CH3:25])([CH3:26])[CH3:27])([CH3:28])[CH3:29])[cH:9][cH:10]1.[CH2:78]1[O:79][CH2:80][CH2:81][CH2:82]1.[CH3:49][CH2:50][CH2:51][CH2:52][N+:53]([CH2:54][CH2:55][CH2:56][CH3:57])([CH2:58][CH2:59][CH2:60][CH3:61])[CH2:62][CH2:63][CH2:64][CH3:65].[CH3:66][CH2:67][O:68][C:69](=[O:70])[CH3:71].[CH3:72][CH2:73][CH2:74][CH2:75][CH2:76][CH3:77].[F-:48]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([S:11](=[O:12])(=[O:13])[NH:14][c:15]2[c:16](-[c:41]3[cH:42][cH:43][c:44]([CH3:47])[cH:45][cH:46]3)[c:17]([O:30][CH2:31][CH2:32][O:33][c:34]3[n:35][cH:36][c:37]([Cl:40])[cH:38][n:39]3)[n:18][n:19]2[CH2:20][CH2:21][OH:22])[cH:9][cH:10]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5171f0a255284cfcb1319b668e476284
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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