Dichloromethane → 1-[[(4-Benzoyl-1-piperazinyl)carbonyl]amino]cyclohexanecarboxylic acid phenylmethyl ester

HRID 2122662Notes

Reaction equation

HRID 2122662 reaction equation
[C:18](=[O:19])([O:20][C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32].[C:40]([c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1)(=[O:47])[N:48]1[CH2:49][CH2:50][NH:51][CH2:52][CH2:53]1.[CH2:54]([Cl:55])[Cl:56].[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[c:1]1([CH2:7][O:8][C:9](=[O:10])[C:11]2([NH2:17])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][O:8][C:9](=[O:10])[C:11]2([NH:17][C:18](=[O:19])[N:51]3[CH2:50][CH2:49][N:48]([C:40]([c:41]4[cH:42][cH:43][cH:44][cH:45][cH:46]4)=[O:47])[CH2:53][CH2:52]3)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 90495Di-tert-butyl dicarbonateHCID 7626541-BenzoylpiperazineHCID 15176238Benzyl 1-aminocyclohexanecarboxylate

Product 1

HCID 576729161-[[(4-Benzoyl-1-piperazinyl)carbonyl]amino]cyclohexanecarboxylic acid phenylmethyl ester

Sources & evidence

ORD record
ord-3846fc5fdf144e578a4166e2f48feb75
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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