Hydrochloric Acid → 2-chloro-7-(4-chlorophenyl)-4-(3,3-difluoroazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine
Reaction equation
[CH2:19]([N:20]([CH:21]([CH3:22])[CH3:23])[CH:24]([CH3:25])[CH3:26])[CH3:27].[CH3:35][OH:36].[Cl:1][c:2]1[n:3][c:4]([Cl:18])[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]1)[CH2:9][CH2:10]2.[ClH:34].[F:28][C:29]1([F:33])[CH2:30][NH:31][CH2:32]1>>[Cl:1][c:2]1[n:3][c:4]([N:31]2[CH2:30][C:29]([F:28])([F:33])[CH2:32]2)[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]1)[CH2:9][CH2:10]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1a72b3344afc41aca46d74c770725322
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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