Hydrochloric Acid → 3-[[1-(morpholine-4-carbonyl)pyrrolidin-3-yl]methyl]-4-(4-quinolin-7-ylphenyl)-1H-1,2,4-triazol-5-one

HRID 2123308Notes

Reaction equation

HRID 2123308 reaction equation
[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:48][CH2:49][Cl:50].[ClH:1].[NH:2]1[CH2:3][CH:4]([CH2:7][c:8]2[n:9](-[c:14]3[cH:15][cH:16][c:17](-[c:20]4[cH:21][cH:22][c:23]5[cH:24][cH:25][cH:26][n:27][c:28]5[cH:29]4)[cH:18][cH:19]3)[c:10](=[O:13])[nH:11][n:12]2)[CH2:5][CH2:6]1.[O:39]1[CH2:40][CH2:41][N:42]([C:45](=[O:46])[Cl:47])[CH2:43][CH2:44]1>>[N:2]1([C:45]([N:42]2[CH2:41][CH2:40][O:39][CH2:44][CH2:43]2)=[O:46])[CH2:3][CH:4]([CH2:7][c:8]2[n:9](-[c:14]3[cH:15][cH:16][c:17](-[c:20]4[cH:21][cH:22][c:23]5[cH:24][cH:25][cH:26][n:27][c:28]5[cH:29]4)[cH:18][cH:19]3)[c:10](=[O:13])[nH:11][n:12]2)[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 848104-Morpholinecarbonyl chlorideHCID 178518804HCID 178518804, compound

Product 1

HCID 673562463-[[1-(morpholine-4-carbonyl)pyrrolidin-3-yl]methyl]-4-(4-quinolin-7-ylphenyl)-1H-1,2,4-triazol-5-one

Sources & evidence

ORD record
ord-89c69a6a44fa482792a617a1198d89bf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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