Tetrahydrofuran → 1-[3-(1,3-Difluoro-2-methylpropan-2-yl)isoxazol-5-yl]-3-[3-(6,7-dimethoxyquinazolin-4-ylthio)phenyl]urea
Reaction equation
[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:22][O:23][c:24]1[cH:25][c:26]2[c:27]([S:36][c:37]3[cH:38][c:39]([NH2:40])[cH:41][cH:42][cH:43]3)[n:28][cH:29][n:30][c:31]2[cH:32][c:33]1[O:34][CH3:35].[CH:44]([N:45]([CH2:46][CH3:47])[CH:48]([CH3:49])[CH3:50])([CH3:51])[CH3:52].[F:1][CH2:2][C:3]([CH2:4][F:5])([CH3:6])[c:7]1[n:8][o:9][c:10]([NH:12][C:13]([O:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)=[O:21])[cH:11]1>>[F:1][CH2:2][C:3]([CH2:4][F:5])([CH3:6])[c:7]1[n:8][o:9][c:10]([NH:12][C:13](=[O:21])[NH:40][c:39]2[cH:38][c:37]([S:36][c:27]3[c:26]4[cH:25][c:24]([O:23][CH3:22])[c:33]([O:34][CH3:35])[cH:32][c:31]4[n:30][cH:29][n:28]3)[cH:43][cH:42][cH:41]2)[cH:11]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f971db9641824e059fb0fc0469584bad
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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