Ethanol → 2'-azido-7'-methoxyspiro[5H-1,3-oxazole-4,9'-xanthene]-2-amine

HRID 2123676Notes

Reaction equation

HRID 2123676 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([O:21][CH3:22])[cH:13][c:14]1[C:15]21[N:16]=[C:17]([NH2:20])[O:18][CH2:19]1.[CH3:27][NH:28][CH:29]1[CH2:30][CH2:31][CH2:32][CH2:33][CH:34]1[NH:35][CH3:36].[CH3:37][CH2:38][OH:39].[Cu:41][I:42].[N-:24]=[N+:25]=[N-:26].[Na+:23].[OH2:40]>>[c:2]1([N:24]=[N+:25]=[N-:26])[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([O:21][CH3:22])[cH:13][c:14]1[C:15]21[N:16]=[C:17]([NH2:20])[O:18][CH2:19]1

Participants

8

Reactant 7

HCID 702EthanolHCID 923Sodium ionHCID 962WaterHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 33558AzideHCID 5510741-N,2-N-dimethylcyclohexane-1,2-diamineHCID 584661972'-Bromo-7'-methoxyspiro[1,3-oxazole-4,9'-xanthen]-2-amine

Product 1

HCID 592723682'-azido-7'-methoxyspiro[5H-1,3-oxazole-4,9'-xanthene]-2-amine

Sources & evidence

ORD record
ord-7c1f31386a02430897e4d1d08aaa75ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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