Dichloromethane → 2-((5-(4-amino-6-methyl-1,3,5-triazin-2-yl)-6-(6-methoxypyridin-3-ylamino)pyridin-3-yl)(hydroxy)methyl)-4-bromo-N,N-dimethylbenzenesulfonamide
Reaction equation
[CH2:64]([SiH:65]([CH2:66][CH3:67])[CH2:68][CH3:69])[CH3:70].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]([c:9]2[n:10][c:11](-[c:16]3[cH:17][c:18]([CH:31]([c:32]4[c:33]([S:39](=[O:40])(=[O:41])[N:42]([CH3:43])[CH3:44])[cH:34][cH:35][c:36]([Br:38])[cH:37]4)[OH:45])[cH:19][n:20][c:21]3[NH:22][c:23]3[cH:24][n:25][c:26]([O:29][CH3:30])[cH:27][cH:28]3)[n:12][c:13]([CH3:15])[n:14]2)[CH2:46][c:47]2[cH:48][cH:49][c:50]([O:51][CH3:52])[cH:53][cH:54]2)[cH:55][cH:56]1.[Cl:71][CH2:72][Cl:73].[F:57][C:58]([F:59])([F:60])[C:61]([OH:62])=[O:63]>>[NH2:8][c:9]1[n:10][c:11](-[c:16]2[cH:17][c:18]([CH:31]([c:32]3[c:33]([S:39](=[O:40])(=[O:41])[N:42]([CH3:43])[CH3:44])[cH:34][cH:35][c:36]([Br:38])[cH:37]3)[OH:45])[cH:19][n:20][c:21]2[NH:22][c:23]2[cH:24][n:25][c:26]([O:29][CH3:30])[cH:27][cH:28]2)[n:12][c:13]([CH3:15])[n:14]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-82dcffba949944ccab6953671c0f5999
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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