Dimethylformamide → 4-{3-[1-(2,6-Dichloro-3-fluorophenyl)ethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-3,6-dihydro-2H-pyridine-1-carboxamide
Reaction equation
[CH3:27][Si:28]([CH3:29])([CH3:30])[N:31]=[C:32]=[O:33].[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[c:12]2[cH:13][nH:14][c:15]3[n:16][cH:17][c:18]([C:21]4=[CH:26][CH2:25][NH:24][CH2:23][CH2:22]4)[cH:19][c:20]23)[c:4]([Cl:9])[cH:5][cH:6][c:7]1[F:8].[O:43]=[CH:44][N:45]([CH3:46])[CH3:47]>>[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[c:12]2[cH:13][nH:14][c:15]3[n:16][cH:17][c:18]([C:21]4=[CH:26][CH2:25][N:24]([C:32]([NH2:31])=[O:33])[CH2:23][CH2:22]4)[cH:19][c:20]23)[c:4]([Cl:9])[cH:5][cH:6][c:7]1[F:8]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-00074a5e7a184bce8dab4106d53e1232
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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