1-Butanol → 4-amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(1H-pyrazolo[5,4-d]pyrimidin-4-yl)piperidine-4-carboxamide
Reaction equation
[CH3:41][CH2:42][CH2:43][CH2:44][OH:45].[CH3:46][CH2:47][O:48][C:49]([CH3:50])=[O:51].[CH:1]([N:2]([CH2:3][CH3:4])[CH:5]([CH3:6])[CH3:7])([CH3:8])[CH3:9].[Cl:31][c:32]1[c:33]2[c:34]([n:35][cH:36][n:37]1)[nH:38][n:39][cH:40]2.[NH2:10][C:11]1([C:17](=[O:18])[NH:19][CH:20]([CH2:21][CH2:22][OH:23])[c:24]2[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]2)[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1>>[NH2:10][C:11]1([C:17](=[O:18])[NH:19][CH:20]([CH2:21][CH2:22][OH:23])[c:24]2[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]2)[CH2:12][CH2:13][N:14]([c:32]2[c:33]3[c:34]([n:35][cH:36][n:37]2)[nH:38][n:39][cH:40]3)[CH2:15][CH2:16]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-74a47ef421e1421590f0aa62ff65ff63
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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