Ammonium → [2,6-difluoro-3-(propane-1-sulfonylamino)-benzyl]-5-[hydroxy-(1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-methyl]-pyridin-2-yl-carbamic acid tert-butyl ester
Reaction equation
[C:26]([CH3:27])([CH3:28])([CH3:29])[O:30][C:31]([N:32]([c:33]1[n:34][cH:35][c:36]([CH:39]=[O:40])[cH:37][cH:38]1)[CH2:41][c:42]1[c:43]([F:56])[c:44]([NH:49][S:50](=[O:51])(=[O:52])[CH2:53][CH2:54][CH3:55])[cH:45][cH:46][c:47]1[F:48])=[O:57].[CH:22]([Mg+:23])([CH3:24])[CH3:25].[Cl-:21].[Cl-:58].[I:1][c:2]1[cH:3][n:4]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[c:5]2[n:6][cH:7][cH:8][cH:9][c:10]12.[NH4+:59].[O:60]1[CH2:61][CH2:62][CH2:63][CH2:64]1>>[c:2]1([CH:39]([c:36]2[cH:35][n:34][c:33]([N:32]([C:31]([O:30][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:57])[CH2:41][c:42]3[c:43]([F:56])[c:44]([NH:49][S:50](=[O:51])(=[O:52])[CH2:53][CH2:54][CH3:55])[cH:45][cH:46][c:47]3[F:48])[cH:38][cH:37]2)[OH:40])[cH:3][n:4]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[c:5]2[n:6][cH:7][cH:8][cH:9][c:10]12Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c3f6287e77fd4bf5858d78a64af229da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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