Dimethylformamide → Methyl alpha-phenyl-1-[4-[[[4'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl]carbonyl]amino]phenyl]-4-piperidineacetate
Reaction equation
[CH:48]([N:49]([CH2:50][CH3:51])[CH:52]([CH3:53])[CH3:54])([CH3:55])[CH3:56].[Cl:57][CH2:58][Cl:59].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([C:15](=[O:16])[OH:17])[cH:11][cH:12][cH:13][cH:14]2)[cH:7][cH:8]1)([F:18])[F:19].[NH2:24][c:25]1[cH:26][cH:27][c:28]([N:31]2[CH2:32][CH2:33][CH:34]([CH:37]([C:38](=[O:39])[O:40][CH3:41])[c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[CH2:35][CH2:36]2)[cH:29][cH:30]1.[O:60]=[CH:61][N:62]([CH3:63])[CH3:64].[S:20]([Cl:21])([Cl:22])=[O:23]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([C:15](=[O:16])[NH:24][c:25]3[cH:26][cH:27][c:28]([N:31]4[CH2:32][CH2:33][CH:34]([CH:37]([C:38](=[O:39])[O:40][CH3:41])[c:42]5[cH:43][cH:44][cH:45][cH:46][cH:47]5)[CH2:35][CH2:36]4)[cH:29][cH:30]3)[cH:11][cH:12][cH:13][cH:14]2)[cH:7][cH:8]1)([F:18])[F:19]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e2ccb09ede824f5f8f87c69f3c4985c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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