Acetonitrile → 5-(2-chloropyrimidin-4-yloxy)-4-fluoro-2-methyl-1H-indole
Reaction equation
[CH2:1]1[CH2:2][CH2:3][C:4]2=[N:9][CH2:8][CH2:7][CH2:6][N:5]2[CH2:10][CH2:11]1.[CH3:32][C:33]#[N:34].[Cl:24][c:25]1[n:26][cH:27][cH:28][c:29]([Cl:31])[n:30]1.[F:12][c:13]1[c:14]2[cH:15][c:16]([CH3:23])[nH:17][c:18]2[cH:19][cH:20][c:21]1[OH:22]>>[F:12][c:13]1[c:14]2[cH:15][c:16]([CH3:23])[nH:17][c:18]2[cH:19][cH:20][c:21]1[O:22][c:29]1[cH:28][cH:27][n:26][c:25]([Cl:24])[n:30]1Participants
5
Sources & evidence
- ORD record
- ord-47449bef9bc14f9fb2a3a91754ad3b7c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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