Isopropanol → 7-Acetoxy4-(5-benzyloxy-2-fluoro-4-methylanilino)-6-methoxyquinazoline
Reaction equation
[C:1]([CH3:2])(=[O:3])[O:4][c:5]1[c:6]([O:16][CH3:17])[cH:7][c:8]2[c:9](=[O:15])[nH:10][cH:11][n:12][c:13]2[cH:14]1.[CH2:27]([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[O:34][c:35]1[c:36]([CH3:43])[cH:37][c:38]([F:42])[c:39]([NH2:40])[cH:41]1.[CH3:48][CH2:49][CH2:50][CH2:51][CH2:52][CH3:53].[CH:44]([OH:45])([CH3:46])[CH3:47].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26].[S:18]([Cl:19])([Cl:20])=[O:21]>>[C:1]([CH3:2])(=[O:3])[O:4][c:5]1[c:6]([O:16][CH3:17])[cH:7][c:8]2[c:9]([NH:40][c:39]3[c:38]([F:42])[cH:37][c:36]([CH3:43])[c:35]([O:34][CH2:27][c:28]4[cH:29][cH:30][cH:31][cH:32][cH:33]4)[cH:41]3)[n:10][cH:11][n:12][c:13]2[cH:14]1Participants
7
Sources & evidence
- ORD record
- ord-38d70f78fdef4e9abf39c8c6eebb97ab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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