Methanol → 1-(2,6-Dichloro-5-fluoro-4-pyrimidinyl)-3-methyl-3-pyrrolidinol
Reaction equation
[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:11][CH2:12][N:13]([CH2:14][CH3:15])[CH2:16][CH3:17].[CH3:18][C:19]1([OH:24])[CH2:20][NH:21][CH2:22][CH2:23]1.[CH3:30][OH:31].[Cl:1][c:2]1[n:3][c:4]([Cl:10])[c:5]([F:9])[c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][c:4]([N:21]2[CH2:20][C:19]([CH3:18])([OH:24])[CH2:23][CH2:22]2)[c:5]([F:9])[c:6]([Cl:8])[n:7]1Participants
6
Sources & evidence
- ORD record
- ord-2cd3a1ad87bd48ff809bbb1c9e1919ef
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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