HRID2126293

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID11776

Triphenylphosphine

C18H15P

HCID67184

1-Bromopyrrolidine-2,5-dione

C4H4BrNO2

HCID58993672

未命名化合物

PRODUCTS

生成物

结构：N#Cc1ccc(-c2cc(CBr)cc(C(F)(F)F)c2)cc1

HCID58993490

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8fdbd3ad5cfb4f70a2ceef655dfb1a9a
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (4/10)

反应 SMILES

[Br:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[OH:9][CH2:10][c:11]1[cH:12][c:13](-[c:21]2[cH:22][cH:23][c:24]([C:27]#[N:28])[cH:25][cH:26]2)[cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]1.[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[Br:1][CH2:10][c:11]1[cH:12][c:13](-[c:21]2[cH:22][cH:23][c:24]([C:27]#[N:28])[cH:25][cH:26]2)[cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]1