Tetrahydrofuran → Tert-butyl 4-[6-bromo-2-(4-morpholin-4-ylanilino)quinazolin-7-yl]oxypiperidine-1-carboxylate
Reaction equation
[Br:34][c:35]1[cH:36][c:37]2[cH:38][n:39][c:40]([NH:46][c:47]3[cH:48][cH:49][c:50]([N:53]4[CH2:54][CH2:55][O:56][CH2:57][CH2:58]4)[cH:51][cH:52]3)[n:41][c:42]2[cH:43][c:44]1[OH:45].[C:20](=[O:21])([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[N:27]1[CH2:28][CH2:29][CH:30]([OH:33])[CH2:31][CH2:32]1.[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[C:20](=[O:21])([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[N:27]1[CH2:28][CH2:29][CH:30]([O:33][c:44]2[c:35]([Br:34])[cH:36][c:37]3[cH:38][n:39][c:40]([NH:46][c:47]4[cH:48][cH:49][c:50]([N:53]5[CH2:54][CH2:55][O:56][CH2:57][CH2:58]5)[cH:51][cH:52]4)[n:41][c:42]3[cH:43]2)[CH2:31][CH2:32]1Participants
5
Sources & evidence
- ORD record
- ord-d57e38e5ba3e455dbf038c6c4705d879
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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