Hydrogen Bromide → 8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide

HRID 2127320Notes

Reaction equation

HRID 2127320 reaction equation
[Br:2][CH:3]([CH3:4])[c:5]1[cH:6][c:7]([C:22](=[O:23])[N:24]([CH3:25])[CH3:26])[cH:8][c:9]2[c:10](=[O:21])[cH:11][c:12]([N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[o:13][c:14]12.[BrH:1].[F:27][c:28]1[cH:29][c:30]([NH2:31])[cH:32][c:33]([F:35])[cH:34]1.[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[CH:3]([CH3:4])([c:5]1[cH:6][c:7]([C:22](=[O:23])[N:24]([CH3:25])[CH3:26])[cH:8][c:9]2[c:10](=[O:21])[cH:11][c:12]([N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[o:13][c:14]12)[NH:31][c:30]1[cH:29][c:28]([F:27])[cH:34][c:33]([F:35])[cH:32]1

Participants

5

Reactant 4

HCID 260Hydrogen BromideHCID 6228DimethylformamideHCID 965953,5-DifluoroanilineHCID 582349878-(1-bromoethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide

Product 1

HCID 529139298-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide

Sources & evidence

ORD record
ord-1aa8880f068e43c28beccf77327b0122
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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