Methanol → 6-Methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl 3-Methoxy-4-(1-pyrrolidinylmethyl)phenyl Ketone

HRID 2127517Notes

Reaction equation

HRID 2127517 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([C:15](=[O:16])[c:17]2[c:18]3[c:19]([s:20][c:21]2-[c:22]2[cH:23][cH:24][c:25]([O:28][CH2:29][CH2:30][N:31]4[CH2:32][CH2:33][CH2:34][CH2:35]4)[cH:26][cH:27]2)[cH:36][c:37]([OH:40])[cH:38][cH:39]3)[cH:6][cH:7][c:8]1[CH2:9][N:10]1[CH2:11][CH2:12][CH2:13][CH2:14]1.[CH3:50][Si:51]([CH:52]=[N+:53]=[N-:54])([CH3:55])[CH3:56].[CH3:57][OH:58].[CH3:59][OH:60].[CH3:61][C:62]#[N:63].[CH:41]([N:42]([CH:43]([CH3:44])[CH3:45])[CH2:46][CH3:47])([CH3:48])[CH3:49]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([C:15](=[O:16])[c:17]2[c:18]3[c:19]([s:20][c:21]2-[c:22]2[cH:23][cH:24][c:25]([O:28][CH2:29][CH2:30][N:31]4[CH2:32][CH2:33][CH2:34][CH2:35]4)[cH:26][cH:27]2)[cH:36][c:37]([O:40][CH3:41])[cH:38][cH:39]3)[cH:6][cH:7][c:8]1[CH2:9][N:10]1[CH2:11][CH2:12][CH2:13][CH2:14]1

Participants

6

Reactant 5

HCID 887Methanol2×HCID 6342AcetonitrileHCID 81531DiisopropylethylamineHCID 167693TrimethylsilyldiazomethaneHCID 10650441HCID 10650441, compound

Product 1

HCID 211826496-Methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl 3-Methoxy-4-(1-pyrrolidinylmethyl)phenyl Ketone

Sources & evidence

ORD record
ord-28a7f07fee454b1e81aae0e253bc6da6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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