1-Butanol → tert-Butyl 2-({6-[(2-{4-[(biphenyl-2-ylcarbamoyl)oxy]piperidin-1-yl}ethyl)(methyl)amino]-6-oxohexyl}amino)-4-methyl-1,3-thiazole-5-carboxylate
Reaction equation
[Br:1][c:2]1[s:3][c:4]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[c:5]([CH3:7])[n:6]1.[CH2:58]([OH:59])[CH2:60][CH2:61][CH3:62].[CH3:51][CH2:52][N:53]([CH2:54][CH3:55])[CH2:56][CH3:57].[ClH:15].[ClH:16].[c:17]1(-[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:18]([NH:23][C:24]([O:25][CH:26]2[CH2:27][CH2:28][N:29]([CH2:32][CH2:33][N:34]([CH3:35])[C:36]([CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][NH2:42])=[O:43])[CH2:30][CH2:31]2)=[O:44])[cH:19][cH:20][cH:21][cH:22]1>>[c:2]1([NH:42][CH2:41][CH2:40][CH2:39][CH2:38][CH2:37][C:36]([N:34]([CH2:33][CH2:32][N:29]2[CH2:28][CH2:27][CH:26]([O:25][C:24]([NH:23][c:18]3[c:17](-[c:45]4[cH:46][cH:47][cH:48][cH:49][cH:50]4)[cH:22][cH:21][cH:20][cH:19]3)=[O:44])[CH2:31][CH2:30]2)[CH3:35])=[O:43])[s:3][c:4]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[c:5]([CH3:7])[n:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8e0c5ccf560f4e3abafccc1932a3e6b8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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