Tetrahydrofuran → 2,3-Dichloro-N-[5-(hydroxymethyl)-3-methoxy-6-methyl-2-pyrazinyl)benzenesulphonamide
Reaction equation
[CH2:25]([BH-:26]([CH2:27][CH3:28])[CH2:29][CH3:30])[CH3:31].[Cl:1][c:2]1[c:3]([S:9](=[O:10])(=[O:11])[NH:12][c:13]2[n:14][c:15]([CH3:24])[c:16]([C:21](=[O:22])[OH:23])[n:17][c:18]2[O:19][CH3:20])[cH:4][cH:5][cH:6][c:7]1[Cl:8].[Li+:32].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[Cl:1][c:2]1[c:3]([S:9](=[O:10])(=[O:11])[NH:12][c:13]2[n:14][c:15]([CH3:24])[c:16]([CH2:21][OH:22])[n:17][c:18]2[O:19][CH3:20])[cH:4][cH:5][cH:6][c:7]1[Cl:8]Participants
5
Sources & evidence
- ORD record
- ord-6193e2e981bf429dbc50095e1ff912ab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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