Dimethylformamide → 5-Chloro-Thiophene-2-Carboxylic Acid [2-(1--Isopropyl-Piperidin-4-Ylsulfamoyl)-Ethyl]-Amide

HRID 2128649Notes

Reaction equation

HRID 2128649 reaction equation
[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[CH:43]([CH3:44])([CH3:45])[N:46]1[CH2:47][CH2:48][CH:49]([NH:52][S:53](=[O:54])(=[O:55])[CH2:56][CH2:57][NH2:58])[CH2:50][CH2:51]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[OH:9])[s:6]1.[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[P-:10]([F:11])([F:12])([F:13])([F:14])([F:15])[F:16].[n:17]1([O:18][C:19]([N:20]([CH3:21])[CH3:22])=[N+:23]([CH3:24])[CH3:25])[c:26]2[n:27][cH:28][cH:29][cH:30][c:31]2[n:32][n:33]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:9])[NH:58][CH2:57][CH2:56][S:53]([NH:52][CH:49]2[CH2:48][CH2:47][N:46]([CH:43]([CH3:44])[CH3:45])[CH2:51][CH2:50]2)(=[O:54])=[O:55])[s:6]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 950485-Chloro-2-thiophenecarboxylic acidHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 666246312-Amino-ethanesulfonic acid (1-isopropyl-piperidin-4-yl)-amide

Product 1

HCID 119904785-Chloro-Thiophene-2-Carboxylic Acid [2-(1--Isopropyl-Piperidin-4-Ylsulfamoyl)-Ethyl]-Amide

Sources & evidence

ORD record
ord-3e3daba2cde24aee9c28ce8d7c1614b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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