Trifluoroacetic acid → methyl 5-(4-chlorophenyl)-6-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylate

HRID 212871Notes

Reaction equation

HRID 212871 reaction equation
[CH2:26]([SiH:27]([CH2:28][CH3:29])[CH2:30][CH3:31])[CH3:32].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:20]3=[CH:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[c:10]3[c:11]([nH:12]2)[cH:13][c:14]([C:16](=[O:17])[O:18][CH3:19])[s:15]3)[cH:6][cH:7]1.[F:33][C:34]([F:35])([F:36])[C:37]([OH:38])=[O:39]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[c:10]3[c:11]([nH:12]2)[cH:13][c:14]([C:16](=[O:17])[O:18][CH3:19])[s:15]3)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 68467153methyl 5-(4-chlorophenyl)-6-cyclohex-1-en-1-yl-4H-thieno[3,2-b]pyrrole-2-carboxylate

Product 1

HCID 68472408methyl 5-(4-chlorophenyl)-6-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylate

Sources & evidence

ORD record
ord-99e54a3ada284444b21a77e585d6bf3c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…