Tetrahydrofuran → 3-[3-(5-Fluoro-pyridin-2-yl)-5-methyl-isoxazol-4-ylmethoxy]-isothiazole-5-carboxylic acid methyl ester
Reaction equation
[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[CH3:16][O:17][C:18](=[O:19])[c:20]1[cH:21][c:22]([OH:25])[n:23][s:24]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][o:10][c:11]([CH3:15])[c:12]2[CH2:13][OH:14])[n:6][cH:7]1.[O:45]=[C:46]([O:47][CH2:48][CH3:49])[N:50]=[N:51][C:52]([O:53][CH2:54][CH3:55])=[O:56].[c:26]1([P:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:40][cH:41][cH:42][cH:43][cH:44]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][o:10][c:11]([CH3:15])[c:12]2[CH2:13][O:14][c:22]2[cH:21][c:20]([C:18]([O:17][CH3:16])=[O:19])[s:24][n:23]2)[n:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4c6f882b3cf64e32af568373ee297a51
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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