Chloroform → Tert-butyl (3-tosyl-cyclobutyl)-carbamate

HRID 2128930Notes

Reaction equation

HRID 2128930 reaction equation
[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH:32]([Cl:33])([Cl:34])[Cl:35].[OH:1][CH:2]1[CH2:3][CH:4]([NH:6][C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:5]1.[S:21](=[O:22])(=[O:23])([c:24]1[cH:25][cH:26][c:27]([CH3:28])[cH:29][cH:30]1)[Cl:31]>>[CH:2]1([S:21](=[O:22])(=[O:23])[c:24]2[cH:25][cH:26][c:27]([CH3:28])[cH:29][cH:30]2)[CH2:3][CH:4]([NH:6][C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:5]1

Participants

5

Reactant 4

HCID 6212ChloroformHCID 73974-Toluenesulfonyl chlorideHCID 8471TriethylamineHCID 22594430tert-Butyl (3-hydroxycyclobutyl)carbamate

Product 1

HCID 86606183Tert-butyl (3-tosyl-cyclobutyl)-carbamate

Sources & evidence

ORD record
ord-e298325ee1414956beb2dbc0bec4cace
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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