1,2-Dichloroethane → 1,3-Dihydro-3-(RS)-(5-methoxyindole-2-carbonylamino)-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one
Reaction equation
[CH2:35]([Cl:36])[CH2:37][Cl:38].[CH2:46]([Cl:47])[Cl:48].[CH3:21][O:22][c:23]1[cH:24][c:25]2[cH:26][c:27]([C:32](=[O:33])[OH:34])[nH:28][c:29]2[cH:30][cH:31]1.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[NH2:1][CH:2]1[C:3](=[O:20])[NH:4][c:5]2[c:6]([cH:16][cH:17][cH:18][cH:19]2)[C:7]([c:9]2[c:10]([F:15])[cH:11][cH:12][cH:13][cH:14]2)=[N:8]1>>[NH:1]([CH:2]1[C:3](=[O:20])[NH:4][c:5]2[c:6]([cH:16][cH:17][cH:18][cH:19]2)[C:7]([c:9]2[c:10]([F:15])[cH:11][cH:12][cH:13][cH:14]2)=[N:8]1)[C:32]([c:27]1[cH:26][c:25]2[cH:24][c:23]([O:22][CH3:21])[cH:31][cH:30][c:29]2[nH:28]1)=[O:33]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6898aadbee2143dbbf0ea429364602eb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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