Hydrochloric Acid → 1-[5-chloro-3-[2-methoxy-5-(2-piperazin-1-ylethyl)phenyl]-1-[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl-2-oxoindol-3-yl]-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Reaction equation
[CH3:68][CH2:69][O:70][C:71]([CH3:72])=[O:73].[Cl:2][c:3]1[cH:4][c:5]2[c:9]([cH:10][cH:11]1)[N:8]([S:12](=[O:13])(=[O:14])[c:15]1[c:16]([O:23][C:24]([F:25])([F:26])[F:27])[cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]1)[C:7](=[O:28])[C:6]2([N:29]1[CH:30]([C:35](=[O:36])[N:37]([CH3:38])[CH3:39])[CH2:31][CH:32]([OH:34])[CH2:33]1)[c:40]1[cH:41][c:42]([CH2:48][CH2:49][N:50]2[CH2:51][CH2:52][N:53]([C:56]([O:57][C:58]([CH3:59])([CH3:60])[CH3:61])=[O:62])[CH2:54][CH2:55]2)[cH:43][cH:44][c:45]1[O:46][CH3:47].[ClH:1].[Na+:67].[O-:63][C:64]([OH:65])=[O:66]>>[Cl:2][c:3]1[cH:4][c:5]2[c:9]([cH:10][cH:11]1)[N:8]([S:12](=[O:13])(=[O:14])[c:15]1[c:16]([O:23][C:24]([F:25])([F:26])[F:27])[cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]1)[C:7](=[O:28])[C:6]2([N:29]1[CH:30]([C:35](=[O:36])[N:37]([CH3:38])[CH3:39])[CH2:31][CH:32]([OH:34])[CH2:33]1)[c:40]1[cH:41][c:42]([CH2:48][CH2:49][N:50]2[CH2:51][CH2:52][NH:53][CH2:54][CH2:55]2)[cH:43][cH:44][c:45]1[O:46][CH3:47]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ed37c913a5744a339dfd54eb764e5691
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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