Tetrahydrofuran → Methyl 2-[(4-aminophenyl)methyl]-4-chloro-6-(dimethylamino)-5-pyrimidineacetate
Reaction equation
[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:33][CH2:34][O:35][C:36]([CH3:37])=[O:38].[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44].[Cl:1][c:2]1[n:3][c:4]([CH2:16][c:17]2[cH:18][cH:19][c:20]([N+:23]([O-:24])=[O:25])[cH:21][cH:22]2)[n:5][c:6]([N:13]([CH3:14])[CH3:15])[c:7]1[CH2:8][C:9](=[O:10])[O:11][CH3:12].[H:26][H:27]>>[Cl:1][c:2]1[n:3][c:4]([CH2:16][c:17]2[cH:18][cH:19][c:20]([NH2:23])[cH:21][cH:22]2)[n:5][c:6]([N:13]([CH3:14])[CH3:15])[c:7]1[CH2:8][C:9](=[O:10])[O:11][CH3:12]Participants
6
Sources & evidence
- ORD record
- ord-880069e4a353471aba0dd3ec2df23cec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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