Bicarbonate Ion → 3'-Bromo-2-methoxybiphenyl

HRID 2130754Notes

Reaction equation

HRID 2130754 reaction equation
[Br:12][c:13]1[cH:14][cH:15][cH:16][c:17]([Br:19])[cH:18]1.[C:20](=[O:21])([OH:22])[O-:23].[CH3:1][O:2][c:3]1[c:4]([B:9]([OH:10])[OH:11])[cH:5][cH:6][cH:7][cH:8]1.[CH3:25][O:26][CH2:27][CH2:28][O:29][CH3:30].[Na+:24].[OH2:31].[Pd:32]([Cl:33])[Cl:34].[c:35]1([P:36]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[cH:49][cH:50][cH:51][cH:52][cH:53]1.[c:54]1([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[cH:68][cH:69][cH:70][cH:71][cH:72]1>>[CH3:1][O:2][c:3]1[c:4](-[c:17]2[cH:16][cH:15][cH:14][c:13]([Br:12])[cH:18]2)[cH:5][cH:6][cH:7][cH:8]1

Participants

9

Reactant 8

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 79271,3-DibromobenzeneHCID 80711,2-DimethoxyethaneHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 27339582-Methoxyphenylboronic acid

Product 1

HCID 186686213'-Bromo-2-methoxybiphenyl

Sources & evidence

ORD record
ord-9b451f7768864394975d433b1215b90f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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