Dimethylformamide → Diethyl (7,8-difluoro-3-methyl-3,4-dihydro-2H-[1,4]benzoxazine-4-yl)methylenemalonate

HRID 2131272Notes

Reaction equation

HRID 2131272 reaction equation
[CH2:14]([O:15][CH:17]=[C:18]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH3:16].[F:1][c:2]1[c:3]([F:13])[c:4]2[c:5]([cH:11][cH:12]1)[NH:6][CH:7]([CH3:10])[CH2:8][O:9]2.[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[F:1][c:2]1[c:3]([F:13])[c:4]2[c:5]([cH:11][cH:12]1)[N:6]([CH:17]=[C:18]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH:7]([CH3:10])[CH2:8][O:9]2

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 6871Diethyl (ethoxymethylene)malonateHCID 102197187,8-Difluoro-2,3-dihydro-3-methyl-4H-(1,4)benzoxazine

Product 1

HCID 13364401Diethyl (7,8-difluoro-3-methyl-3,4-dihydro-2H-[1,4]benzoxazine-4-yl)methylenemalonate

Sources & evidence

ORD record
ord-e010dcadd83b439abd4ee270883141d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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