Tetrahydrofuran → N-benzyl-2-(3-(2,2-dimethoxyethyl)-3-(4-fluorophenyl)ureido)-4-methylthiazole-5-carboxamide

HRID 2131419Notes

Reaction equation

HRID 2131419 reaction equation
[C:18](=[O:19])([n:20]1[cH:21][cH:22][n:23][cH:24]1)[n:25]1[cH:26][cH:27][n:28][cH:29]1.[CH3:30][O:31][CH:32]([CH2:33][NH:34][c:35]1[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]1)[O:42][CH3:43].[NH2:1][c:2]1[s:3][c:4]([C:8](=[O:9])[NH:10][CH2:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[c:5]([CH3:7])[n:6]1.[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[NH:1]([c:2]1[s:3][c:4]([C:8](=[O:9])[NH:10][CH2:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[c:5]([CH3:7])[n:6]1)[C:18](=[O:19])[N:34]([CH2:33][CH:32]([O:31][CH3:30])[O:42][CH3:43])[c:35]1[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 682631,1'-CarbonyldiimidazoleHCID 210824N-Benzyl-2-imino-4-methyl-2,3-dihydro-1,3-thiazole-5-carboximidic acidHCID 63686639N-(2,2-dimethoxyethyl)-4-fluoroaniline

Product 1

HCID 86645283N-benzyl-2-(3-(2,2-dimethoxyethyl)-3-(4-fluorophenyl)ureido)-4-methylthiazole-5-carboxamide

Sources & evidence

ORD record
ord-f95ffba864b94bdb92ecb16250dfea00
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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