Dimethylformamide → 3-[1-[tert-butyl(dimethyl)silyl]oxypropan-2-yloxy]-N-(1-methylpyrazol-3-yl)-5-phenylmethoxybenzamide

HRID 2131450Notes

Reaction equation

HRID 2131450 reaction equation
[CH3:39][n:40]1[n:41][c:42]([NH2:45])[cH:43][cH:44]1.[CH:1]([N:2]([CH2:3][CH3:4])[CH:5]([CH3:6])[CH3:7])([CH3:8])[CH3:9].[O:70]=[CH:71][N:72]([CH3:73])[CH3:74].[P-:46]([F:47])([F:48])([F:49])([F:50])([F:51])[F:52].[c:10]1([CH2:16][O:17][c:18]2[cH:19][c:20]([C:21](=[O:22])[OH:23])[cH:24][c:25]([O:27][CH:28]([CH2:29][O:30][Si:31]([CH3:32])([CH3:33])[C:34]([CH3:35])([CH3:36])[CH3:37])[CH3:38])[cH:26]2)[cH:11][cH:12][cH:13][cH:14][cH:15]1.[n:53]1([O:54][C:55]([N:56]([CH3:57])[CH3:58])=[N+:59]([CH3:60])[CH3:61])[c:62]2[n:63][cH:64][cH:65][cH:66][c:67]2[n:68][n:69]1>>[c:10]1([CH2:16][O:17][c:18]2[cH:19][c:20]([C:21](=[O:22])[NH:45][c:42]3[n:41][n:40]([CH3:39])[cH:44][cH:43]3)[cH:24][c:25]([O:27][CH:28]([CH2:29][O:30][Si:31]([CH3:32])([CH3:33])[C:34]([CH3:35])([CH3:36])[CH3:37])[CH3:38])[cH:26]2)[cH:11][cH:12][cH:13][cH:14][cH:15]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 1372541-Methyl-3-aminopyrazoleHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 685733253-[1-[Tert-butyl(dimethyl)silyl]oxypropan-2-yloxy]-5-phenylmethoxybenzoic acid

Product 1

HCID 671581093-[1-[tert-butyl(dimethyl)silyl]oxypropan-2-yloxy]-N-(1-methylpyrazol-3-yl)-5-phenylmethoxybenzamide

Sources & evidence

ORD record
ord-a2236ca816a14640a49fd7215d72e8de
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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