Dichloromethane → HCID 5278407, compound

HRID 2131635Notes

Reaction equation

HRID 2131635 reaction equation
[CH2:32]([C:33]#[CH:34])[OH:35].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[cH:11][n:12]([CH3:29])[c:13]3[c:14]([I:28])[cH:15][c:16]([CH2:21][CH:22]4[CH2:23][CH2:24][O:25][CH2:26][CH2:27]4)[cH:17][c:18]3[c:19]2=[O:20])[cH:30][cH:31]1.[Cl:36][CH2:37][Cl:38].[Cu:80][I:81].[Pd:39]([Cl:40])[Cl:41].[c:42]1([P:43]([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[cH:56][cH:57][cH:58][cH:59][cH:60]1.[c:61]1([P:62]([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[cH:75][cH:76][cH:77][cH:78][cH:79]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[cH:11][n:12]([CH3:29])[c:13]3[c:14]([C:34]#[C:33][CH2:32][OH:35])[cH:15][c:16]([CH2:21][CH:22]4[CH2:23][CH2:24][O:25][CH2:26][CH2:27]4)[cH:17][c:18]3[c:19]2=[O:20])[cH:30][cH:31]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 7859Propargyl alcoholHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 22724547HCID 22724547, compound

Product 1

HCID 5278407HCID 5278407, compound

Sources & evidence

ORD record
ord-d97555c09bb34e48868545b03b309b69
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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