4-Methylpyridine → 1-(4-Fluorophenyl)-2-(pyridin-4-yl)ethan-1-one
Reaction equation
[CH3:1][c:2]1[cH:3][cH:4][n:5][cH:6][cH:7]1.[CH3:20][Si:21]([N-:22][Si:23]([CH3:24])([CH3:25])[CH3:26])([CH3:27])[CH3:28].[CH3:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35].[F:8][c:9]1[cH:10][cH:11][c:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:18][cH:19]1.[Li+:29].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[CH2:1]([c:2]1[cH:3][cH:4][n:5][cH:6][cH:7]1)[C:13]([c:12]1[cH:11][cH:10][c:9]([F:8])[cH:19][cH:18]1)=[O:14]Participants
7
Sources & evidence
- ORD record
- ord-7fdae093f2f8465780f20926a26e90c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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