Diethyl Ether → 4-p-Tolyloxy-1H-indole-2-carboxylic acid ethyl ester

HRID 2132575Notes

Reaction equation

HRID 2132575 reaction equation
[CH2:8]([CH3:9])[O:10][C:11](=[O:12])[c:13]1[nH:14][c:15]2[cH:16][cH:17][cH:18][c:19]([O:22][c:23]3[c:24]([NH2:30])[cH:25][c:26]([CH3:29])[cH:27][cH:28]3)[c:20]2[cH:21]1.[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[N:1]([O:2][C:3]([CH3:4])([CH3:5])[CH3:6])=[O:7]>>[CH2:8]([CH3:9])[O:10][C:11](=[O:12])[c:13]1[nH:14][c:15]2[cH:16][cH:17][cH:18][c:19]([O:22][c:23]3[cH:24][cH:25][c:26]([CH3:29])[cH:27][cH:28]3)[c:20]2[cH:21]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 10906Tert-Butyl nitriteHCID 668420484-(2-Amino-4-methyl-phenoxy)-1H-indole-2-carboxylic acid ethyl ester

Product 1

HCID 668415404-p-Tolyloxy-1H-indole-2-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-7ad74e07f24a430cb44d44db14e80be4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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