Piperidine → Methyl 4-[3-[[(1,1-dimethylethoxy)carbonyl]amino]-1-propyn-1-yl]benzoate

HRID 2132715Notes

Reaction equation

HRID 2132715 reaction equation
[CH2:12]([C:13]#[CH:14])[NH:15][C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22].[CH2:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1.[CH3:1][O:2][C:3]([c:4]1[cH:5][cH:6][c:7]([I:10])[cH:8][cH:9]1)=[O:11].[Cu:29][I:30]>>[CH3:1][O:2][C:3]([c:4]1[cH:5][cH:6][c:7]([C:14]#[C:13][CH2:12][NH:15][C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[cH:8][cH:9]1)=[O:11]

Participants

5

Reactant 4

HCID 8082PiperidineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 69273Methyl 4-iodobenzoateHCID 11073648tert-butyl N-(prop-2-yn-1-yl)carbamate

Product 1

HCID 18617679Methyl 4-[3-[[(1,1-dimethylethoxy)carbonyl]amino]-1-propyn-1-yl]benzoate

Sources & evidence

ORD record
ord-ac283ffb91464cc3a4a242b37d9e60f9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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