1,2-Dichloroethane → 5-(2,4-Dichlorophenyl)-7-methyl-2-(2-oxo-2-(pyrrolidin-1-yl)ethyl)imidazo[1,2-a]pyrimidine-6-carbonitrile

HRID 2133876Notes

Reaction equation

HRID 2133876 reaction equation
[C:1](#[N:2])[c:3]1[c:4]([CH3:24])[n:5][c:6]2[n:7]([c:8]1-[c:9]1[c:10]([Cl:16])[cH:11][c:12]([Cl:15])[cH:13][cH:14]1)[cH:17][c:18]([CH2:20][C:21](=[O:22])[OH:23])[n:19]2.[CH2:25]([Cl:26])[CH2:27][Cl:28].[CH2:29]1[CH2:30][CH2:31][NH:32][CH2:33]1.[CH3:34][C:35]#[N:36]>>[C:1](#[N:2])[c:3]1[c:4]([CH3:24])[n:5][c:6]2[n:7]([c:8]1-[c:9]1[c:10]([Cl:16])[cH:11][c:12]([Cl:15])[cH:13][cH:14]1)[cH:17][c:18]([CH2:20][C:21](=[O:22])[N:32]1[CH2:31][CH2:30][CH2:29][CH2:33]1)[n:19]2

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 6342AcetonitrileHCID 31268PyrrolidineHCID 579824512-(6-Cyano-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)acetic acid

Product 1

HCID 579824525-(2,4-Dichlorophenyl)-7-methyl-2-(2-oxo-2-(pyrrolidin-1-yl)ethyl)imidazo[1,2-a]pyrimidine-6-carbonitrile

Sources & evidence

ORD record
ord-ed69aa8a71bb4776a9987c3699c3f3d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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