Hydrochloric Acid → 3-carboxy-2-trifluoromethyl-2-hydroxy-4-(3-cyanophenyl)-4,6,7,8-tetrahydro-5 (1H)-quinolone
Reaction equation
[C:1](=[O:2])([O:3][CH2:4][CH3:5])[CH:6]1[C:7]([OH:25])([C:26]([F:27])([F:28])[F:29])[NH:8][C:9]2=[C:14]([C:13](=[O:24])[CH2:12][CH2:11][CH2:10]2)[CH:15]1[c:16]1[cH:17][c:18]([C:22]#[N:23])[cH:19][cH:20][cH:21]1.[CH3:34][CH2:35][OH:36].[ClH:33].[Li+:32].[OH-:31].[OH2:30].[OH2:37]>>[C:1](=[O:2])([OH:3])[CH:6]1[C:7]([OH:25])([C:26]([F:27])([F:28])[F:29])[NH:8][C:9]2=[C:14]([C:13](=[O:24])[CH2:12][CH2:11][CH2:10]2)[CH:15]1[c:16]1[cH:17][c:18]([C:22]#[N:23])[cH:19][cH:20][cH:21]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d0ed5907335d419fa1ce3a9a2e56616b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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