Acetate → N-(2,3-dihydro-1H-inden-1-yl)-5-phenylquinolin-2-amine

HRID 2135167Notes

Reaction equation

HRID 2135167 reaction equation
[C:63]([O-:64])(=[O:65])[CH3:66].[C:68]([O-:69])(=[O:70])[CH3:71].[CH3:50][O:51][CH2:52][CH2:53][O:54][CH3:55].[CH:1]1([NH:10][c:11]2[n:12][c:13]3[cH:14][cH:15][cH:16][c:17]([I:21])[c:18]3[cH:19][cH:20]2)[CH2:2][CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21.[Na+:56].[Na+:57].[O-:58][C:59](=[O:60])[O-:61].[OH2:62].[OH:22][B:23]([OH:24])[c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[Pd+2:67].[c:31]1([P:32]([c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:45][cH:46][cH:47][cH:48][cH:49]1>>[CH:1]1([NH:10][c:11]2[n:12][c:13]3[cH:14][cH:15][cH:16][c:17](-[c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)[c:18]3[cH:19][cH:20]2)[CH2:2][CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21

Participants

10

Reactant 9

HCID 175Acetate2×HCID 923Sodium ion2×HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 66827Phenylboronic AcidHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 67095933N-(2,3-dihydro-1H-inden-1-yl)-5-iodoquinolin-2-amine

Product 1

HCID 67095905N-(2,3-dihydro-1H-inden-1-yl)-5-phenylquinolin-2-amine

Sources & evidence

ORD record
ord-736bbcd593de4568ac4676fb35ab5bf7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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