Dimethylformamide → N-[4-(4-acetamidophenyl)sulfonyl-2-chlorophenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Reaction equation
[C:22]([CH3:23])(=[O:24])[NH:25][c:26]1[cH:27][cH:28][c:29]([S:32](=[O:33])(=[O:34])[c:35]2[cH:36][c:37]([Cl:42])[c:38]([NH2:39])[cH:40][cH:41]2)[cH:30][cH:31]1.[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:43][CH2:44][Cl:45].[O:17]=[CH:18][N:19]([CH3:20])[CH3:21].[OH:7][C:8]([C:9](=[O:10])[OH:11])([C:12]([F:13])([F:14])[F:15])[CH3:16]>>[OH:7][C:8]([C:9](=[O:10])[NH:39][c:38]1[c:37]([Cl:42])[cH:36][c:35]([S:32]([c:29]2[cH:28][cH:27][c:26]([NH:25][C:22]([CH3:23])=[O:24])[cH:31][cH:30]2)(=[O:33])=[O:34])[cH:41][cH:40]1)([C:12]([F:13])([F:14])[F:15])[CH3:16]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cb4b9c999734433d82291525efc4c419
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…